Endocrine Abstracts

A 50 year old Asian lady developed neck pain and sore throat 10 days after first dose of AstraZeneca COVID-19 vaccination. Her dentist thought she had tonsillitis. She then presented to hospital a few days later with dyspnoea, palpitations, tremor and neck pain. She was apyrexial but clinically thyrotoxic with sinus tachycardia. Thyroid gland had normal size with tenderness without bruit or lymphadenopathy. Her Free T4 was >100 pmol/l (11.2 - 20.2), TSH < 0.01mIU/l, ES...

Background: Previous population studies suggest cancer morbidity is different in Turner syndrome (TS) compared to the background female population. Whilst gonadoblastoma is well recognized in TS with Y chromosome material, studies have suggested increased prevalence of skin tumours and meningioma but reduced incidence of breast cancer.Methods: Retrospective analysis of an adult TS clinic patient database identified women who developed cancer. Tumour type...

Introduction: Acromegaly is a rare metabolic condition in adults caused by over secretion of growth hormone from the pituitary gland. The characteristic skeletal and organ overgrowth and dental mal-occlusion issues are so insidious that they go unnoticed by the patient and family. The dentist may be the first healthcare provider to see these patients, thereby proving instrumental in early diagnosis. We report two cases of acromegaly: one case identified by a dentist and anothe...

Background: Patients receiving radiotherapy for residual or recurrent pituitary adenoma require regular surveillance for the development of anterior pituitary axis deficit. Whilst the sequelae of hypopituitarism post cranial irradiation is well recognized, there are relatively varied incidences of new onset hypopituitarism post-conventional radiotherapy, reported in the literature. We aimed to investigate timing and frequency of the individual axis deficits in adults who have ...